Intern/Aide - (Molecular & Human Genetics )
Baylor College of Medicine
Houston, TX
Job posting number: #7329941 (Ref:24952-en_US)
Posted: April 30, 2026
Job Description
Summary
The summer intern will receive training in the design and synthesis of pyrrole-imidazole polyamides, small molecules that target specific DNA repeat sequences. Training will include organic chemistry techniques for solid-phase synthesis, HPLC purification, and mass spectrometry.
Job Purpose
Provides temporary administrative or laboratory support to a department while gaining practical work experience.
Job Duties
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Learn the principles and practice of pyrrole-imidazole polyamide design and synthesis for targeting trinucleotide repeat DNA sequences.
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Gain hands-on experience in mammalian cell culture and drug treatment assays to evaluate repeat-contracting therapeutics.
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Develop skills in experimental design, data analysis, and scientific communication in a translational research context.
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Synthesize pyrrole-imidazole polyamides using solid-phase synthesis methods.
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Purify and characterize compounds via HPLC and mass spectrometry.
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Culture mammalian cell lines and perform drug treatment experiments with polyamide compounds.
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Assess polyamide efficacy using PCR-based repeat sizing, gene expression assays, and cell viability.
- May assist with special projects/programs.
Minimum Qualifications
Must be enrolled in high school, trade/vocational school or higher education institution.
Work Authorization Requirement:
This position is not eligible for visa sponsorship. Candidates must be legally authorized to work in the United States at the time of application and throughout the duration of employment.
Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.
Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. - Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective. - Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve. - Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.
