Summary

Dr. Wei Li’s laboratory in the Department of Ophthalmology at the Cullen Eye Institute, Baylor College of Medicine, is seeking a talented and motivated Postdoctoral Associate. The translational research centers on ligandomics—a novel omics technology developed by the group—for drug target discovery and the development of innovative therapies for ocular diseases that includes glaucoma, diabetic retinopathy, wet age related macular degeneration (AMD), dry AMD, fibrotic and oxidative conditions.

This position will focus on investigating neurovascular regulation in glaucoma. Specifically, the postdoc will functionally validate glaucoma selective endothelial ligands and neurotrophic factors identified through ligandomics to assess their disease selectivity, binding specificity, biological activity, pathogenic roles, and therapeutic potential. These studies will employ a range of biochemical, cellular, and molecular approaches. The long term goal is to develop effective neuroprotective therapies for glaucoma and other neurodegenerative disorders.

Postdoctoral Associate with a strong record of scientific productivity, as evidenced by peer reviewed publications, and a strong commitment to research are desired. Recent recipients of a PhD and/or MD are highly encouraged to apply. Experience in molecular biology, cell biology, protein biochemistry, and/or animal research is strongly desirable. Excellent verbal and written communication skills are required, as the position involves preparing manuscripts and applying for postdoctoral fellowships. The lab offers robust opportunities for career development.

Baylor College of Medicine typically follows similar to the NIH stipulated stipend guidelines for Postdoctoral Associates.

Job Duties

• Focuses on drug target discovery, validation, and therapeutic development for glaucoma.
• Investigates the roles of individual protein targets identified through ligandomics in disease mechanisms and evaluate their therapeutic potential for neuroprotective treatment.
• Works on additional projects in the lab that includes mechanistic studies and therapeutic development for diabetic retinopathy, wet and dry age related macular degeneration (AMD), oxidative stress, and fibrosis.
• Presents research findings, write manuscripts, and prepare postdoctoral fellowship applications.
• Supervises graduate, medical, undergraduate, and high school students.
• Performs other job-related duties as assigned.

Minimum Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

Preferred Qualifications

• Knowledge of ophthalmology and experience in ophthalmic or animal surgery skills are not necessary but a plus.
• Demonstrates scientific productivity with peer-reviewed publications and strong commitment to scientific research.
• Experience in molecular biology, cell biology, protein biochemistry and/or animal research are desired.
• Excellent verbal and written communication skills.